Our 10 year old Great Pyrenees was having a hard time getting up and moving about. She had surgery on both her knees years before and was suffering from arthritis. It was amazing to see how well NatrixOne worked. In addition to an amazing coat (she blew her old coat out within 2 weeks of being on the product and grew back an incredibly soft, pillowy fur!), she is now back to how she was when she was 3 – she has even gone back to her long-neglected box of toys and has been selecting old favorites for us to play with her. I love what it has done for her and the obvious quality of life improvement! Thank you NatrixOne.